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Dr. Gunter Wagner, "Evolution of Gene Regulations as it pertains to the Origin of Evolutionary Novelties"

Date: 09/25/08
Time: 3:30-5:30 p.m.
Audience: Public
Sponsored By: School of Science and Engineering
Location: Coykendall Science Building Lounge and Auditorium
Contact: Dr. Julio Gonzalez, x3724,

There is broad consensus that developmental evolution is based on the evolution of gene regulation. Furthermore there is also broad agreement that evolution of gene regulation is synonymous with the evolution of transcription factor binding sites in cis-regulatory elements. However, recent findings on the evolution of gene regulation in ESC (Endometrial Stromal Cells) during the origin of placental mammals, suggest that gene regulation evolves through a plurality of mechanisms rather than only cis-regulatory nucleotide substitution. It seems that there is no preferred locus for evolution of gene regulation, especially if a novel cell type evolves and novel gene regulatory links arise. Dr. Günter Wagner is the Alison Richard Professor of Ecology and Evolutionary Biology at Yale University. He will present and explain his aforementioned findings and conclusions.